in vitro Test - OECD 471, OECD 473, OECD 476, OECD 487, OECD 490
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INVITRO-CONNECT GmbH can perform for you a complete set of in vitro tests in our GLP-certified cooperation laboratories, which can when required, be complemented by further well-established in vivo tests.
IN VITRO GENOTOXICOLOGY / Mutagenicity Tests in vitro Test Method
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- in vitro gene mutation study in bacteria: Ames Test OECD 471 / OPPTS / ICH
- in vitro gene mutation study in mammalian cells: Mouse Lymphoma Assay (MLTK Assay) OECD 490 /
OPPTS / ICH
- in vitro gene mutation study in mammalian cells: HPRT test / OECD 476 / OPPTS / ICH
- Micronucleus Assay in vitro (Human Lymphocytes or V79 cells) / OECD 487 / OPPTS / ICH
- Chromosomal aberration Assay in vitro (Human Lymphocytes or V79 cells) / OECD 473 / OPPTS / ICH
- Hen’s Egg Test – Induction of Micronuclei (HET-MN)
- COMET Assay in different cell types
iN VITRO DETECTION OF NON-GENOTOXIC CARCINOGENS
- Cell Transformation Assay in Bhas Cells / OECD 231 (draft)
IN VIVO GENOTOXICOLOGY / Mutagenicity Tests in vivo Test Method
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INVITRO-CONNECT GmbH also offers further Tests / IN VIVO GENOTOXICOLOGY.
- Mammalian Erythrocyte Micronucleus Test / OECD 474 / ISO 10993-3
- Combined Mammalian Erythrocyte Micronucleus Test with concurrent Alkaline Comet Assay in vivo
OECD 474 & 489
- In vivo Mammalian Alkaline Comet Assay (several organs on request) / OECD 489
- Unscheduled DNA synthesis (UDS) Test with Mammalian Liver Cells in vivo / OECD 486
- Mammalian Spermatogonial Chromosomal Aberration test / OECD 483
- Mammalian Bone Marrow Chromosomal Aberration test / OECD 475
For more information please contact INVITRO-CONNECT GmbH for assistance in developing specialized protocols for your test materials.
INVITRO-CONNECT GmbH:
Fast Project Execution: personal - competent - reliable --> contact@invitro-connect.com
More than 80 test laboratories - Product safety - Regulatory service - In vitro tests - All OECD tests for pharmaceuticals, chemicals, medical devices and cosmetics - Study monitoring, MSDS etc.